This talk will give a general introduction of Industry Revolution 4.0 (IR 4.0), which including smart product, smart innovation, smart network and smart production. In order to value added not only for the product but also for the partnership in the supply chain, information transparency can be digitalized with IoT (Internet-of-thing) technology for personal requirements, products and services in the future. Therefore, IoT sensors is the key technology for the IR 4.0. In Prof. Chuang’s Lab, a variety of sensors has been developed and implemented in different applications such as Point-of-care device, medical endoscopy, robotics and logistics. All kinds of sensors will be presented in the talk and welcome to discuss about the further collaboration with MANST Lab.